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Cobas Integra 400 Plus

The COBAS INTEGRA 400 plus analyzer is the perfect solution for laboratories running up to 400 samples per day. Its broad test menu comprises over 120 assays and applications that consolidate clinical chemistry with specific proteins, therapeutic drug monitoring and drug abuse testing. This compact tabletop analyzer offers maximum versatility to improve efficiency and reduce costs. It uses the convenient cobas c pack reagent format, which standardizes patient results across integrated laboratory networks.

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Economic efficiency

  • Ready-to-use reagents with a long stability and low calibration effort
  • Simplified processes and reduced costs
  • Comprehensive testing capabilities on a compact footprint

Medical value

  • Four measuring technologies: Absorbance photometry, Turbidimetry, Fluorescence polarimetry, Ion-selective electrode potentiometry
  • Highly correlating results across all cobas® platforms
  • Single-use cuvettes to ensure carry-over free analytics

Ease of use

  • Comprehensive testing capabilities on a compact footprint
  • Continuous loading and random access to samples
  • Refrigerated storage for long calibration stability


  • System Random and continuous access, sample selective analyser
  • Integration of 4 measuring principles
  • 36 tests onboard
  • Absorbance photometry: Enzymes and substrates
  • Ion-selective electrode potentiometry: Na+,K+,Cl– Li+
  • Test throughput Up to 400 tests/hr (including ISE)
  • Sample types Serum, plasma, urine, CSF, hemolysate and whole blood (HbA1c)
  • Automatic sample dilution and concentration
  • Sample volume Typically 2 to 10 µL per test, ISE indirect 20 µL, ISE direct 97 µL